Полиморфизм гена моноаминооксидазы (МАОА) и вариативность психологических черт

Авторы

  • Марина Егорова
  • Юлия Черткова

DOI:

https://doi.org/10.54359/ps.v4i20.807

Ключевые слова:

полиморфизм моноаминооксидазы, генотип-средовое взаимодействие, агрессивность, черты личности

Аннотация

В молекулярно-генетических исследованиях показано, что генетические полиморфизмы (разные варианты одного и того же гена) определяют индивидуальные различия по целому ряду признаков, связанных с патологией, и одновременно – индивидуальные различия по психологическим признакам, варьирующим в пределах нормы. Обзор посвящен исследованиям вариативности психологических признаков, связанной с полиморфизмом гена МАОА, который кодирует фермент моноаминооксидазу, разрушающий моноамины и поддерживающий относительно постоянный уровень моноаминов в тканях. Анализируются исследования, в которых 1) генетическая вариативность рассматривается как одна из причин вариативности отдельных психологических признаков (асоциального поведения, тревожности, депрессивности, диспозиционных черт личности); 2) используется модель генотип-средового взаимодействия (оценивается влияние генетических предпосылок на психологические признаки в зависимости от ситуации развития); 3) рассматривается взаимодействие полиморфизмов гена МАОА с полиморфизмами ряда других генов и их совместное влияние на вариативность психологических признаков.

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Биографии авторов

  • Марина Егорова
    Егорова Марина Сергеевна. Доктор психологических наук, профессор, член-корреспондент Российской академии образования, заведующая кафедрой психогенетики, факультет психологии, Московский государственный университет им. М.В.Ломоносова, ул. Моховая, д. 11, стр. 9, 125009 Москва, Россия. E-mail: ms_egorova@mail.ru
  • Юлия Черткова
    Черткова Юлия Давидовна. Кандидат психологических наук, ассистент кафедры психогенетики, факультет психологии, Московский государственный университет им. М.В.Ломоносова, ул. Моховая, д. 11, стр. 9, 125009 Москва, Россия. E-mail: y_chertkova@mail.ru

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Опубликован

31.12.2011

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Полиморфизм гена моноаминооксидазы (МАОА) и вариативность психологических черт. (2011). Психологические исследования, 4(20). https://doi.org/10.54359/ps.v4i20.807