Psikhologicheskie Issledovaniya • ISSN 2075-7999
peer-reviewed • open access journal
      

 

2017 Vol. 10 Issue 51

Burdukova Y. A., Alekseeva O.S., Andreeva E.V., Popov V.E. Predictors of cognitive deficit in children with brain tumor


BURDUKOVA Y. A., ALEKSEEVA O.S., ANDREEVA E.V., POPOV V.E. PREDICTORS OF COGNITIVE DEFICIT IN CHILDREN WITH BRAIN TUMOR
Full text in Russian: Бурдукова Ю.А., Алексеева О.С., Андреева Е.В., Попов В.Е. Предикторы дефицита когнитивного развития у детей, имеющих в анамнезе нейроонкологическое заболевание

Moscow State University of Psychology and Education, Moscow, Russia
Psychological Institute, Moscow, Russia
Morozov Children's City Clinical Hospital, Moscow, Russia

About authors
Suggested citation


There are a lot of evidences that the negative effects of chemotherapy and  radiotherapy reduce subsequently child's cognitive abilities. Despite of the massive data amount, there are no studies where integrated approach to assessment of anamnesis data influence on cognitive development was used. In this study we investigated the role of anamnesis' factors in the appearance of delayed cognitive deficits in children with brain tumor. The sample included 130 children with lesions of the cerebellum, the pineal regions and parietal-temporal cortical areas. Level of cognitive development was determined by using Kaufman Assessment Battery for Children (K-ABC and K-ABC-II). Kaufman Assessment Battery for Children includes scales: Mental Processing Index, Sequential Processing Scale, Simultaneous Processing Scale, Learning Scale and Planning Scale. Multiple regression analysis was used to evaluate influence of such factors as gender, duration of postoperative period and neuro-oncological disease treatment (chemotherapy and radiotherapy). It was found out that chemotherapy and radiation therapy become determinative factors of delayed cognitive deficiency in children with neuro-oncological diseases only at cerebellar tumor localization. For children with pineal region tumors and parietal-temporal lobe tumors most important negative factors were male sex and early surgical intervention. Girls with lesions of the pineal region and parietal-temporal cortical areas show greater maintenance in verbal memory and planning function in comparison with boys. Such results can be explained by different gender localization of these cognitive functions.

Keywords: predictors of cognitive development, brain tumor, radio- and chemotherapy

 

Funding
The study was supported by the Russian Foundation for Basic Research, project 15-06-08680.


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Received 29 August 2016. Date of publication: 28 February 2017.

About authors

Burdukova Yulia A. Ph.D., Associate Professor, Moscow State University of Psychology and Education, ul. Sretenka, 29, 127051 Moscow, Russia.
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Alekseeva Olga S. Research Associate, Psychological Institute, ul. Mokhovaya, 9–4, 125009 Moscow, Russia.
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Andreeva Elena V. Ph.D., High level certificate physician, Neurologist, Morozov Children's City Clinical Hospital, 4-i Dobryninskii per., 1/9, 119049, Moscow, Russia.
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Popov Vladimir E. Ph.D., High level certificate physician, Head of the Center of Cerebrovascular Pathology, Morozov Children's City Clinical Hospital, 4-i Dobryninskii per., 1/9, 119049, Moscow, Russia.
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Suggested citation

Burdukova Y. A., Alekseeva O.S., Andreeva E.V., Popov V.E. Predictors of cognitive deficit in children with brain tumor. Psikhologicheskie Issledovaniya, 2017, Vol. 10, No. 51, p. 3. http://psystudy.ru (in Russian, abstr. in English).

Permanent URL: http://psystudy.ru/index.php/eng/2017v10n51e/1390-burdukova51e.html

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